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Dexamethasone and Interleukin-1 Potently Synergize to Stimulate the Production of Granulocyte Colony-Stimulating Factor in Differentiated THP-1 Cells

✍ Scribed by Y. Wang; J.J. Zhang; K.Y. Lei; J.W. Pike


Book ID
115581066
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
98 KB
Volume
239
Category
Article
ISSN
0006-291X

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We have studied stromal cell function in naive or interleukin-1 (IL-1)-stimulated (100 pgiml) long-term marrow cultures (LTC) from 1 2 normal donors and 21 patients with severe aplastic anemia (AA). Conditioned media (CM) from normal LTC contained levels of erythroid burst-promoting activity (BPA) a