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Dexamethasone alters messenger RNA levels but not synthesis of collagens, fibronectin, or laminin by cultured rat fat-storing cells

โœ Scribed by T Niki; D Schuppan; PJ de Bleser; R Vrijsen; M Pipeleers-Marichal; R Beyaert; E Wisse; A Geerts


Book ID
118686269
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
401 KB
Volume
23
Category
Article
ISSN
0270-9139

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Dexamethasone alters messenger RNA level
โœ T Niki; D Schuppan; P J de Bleser; R Vrijsen; M Pipeleers-Marichal; R Beyaert; E ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 396 KB ๐Ÿ‘ 1 views

Glucocorticoids have been shown to suppress collagen synthesis and gene expression by fibroblasts. However, little is known about their effects on fat-storing cells, the major matrix-producing cells in liver fibrosis. In this study we investigated the effect of dexamethasone on the extracellular mat