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Developments in Nonsteroidal Antiandrogens Targeting the Androgen Receptor

✍ Scribed by Bo Liu; Lei Su; Jingkun Geng; Junjie Liu; Prof. Guisen Zhao


Book ID
102101092
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
488 KB
Volume
5
Category
Article
ISSN
1860-7179

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## Abstract To study the mechanisms whereby androgen‐dependent tumors relapse in patients undergoing androgen blockade, we developed a novel progression model for prostate cancer. The PC346C cell line, established from a transurethral resection of a primary tumor, expresses wild‐type (wt) androgen