Sequence variations in the flavin-contai
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BASARAB; ASHTON; Du P.MENAGΓ; McGRATH
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Article
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1999
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John Wiley and Sons
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English
β 462 KB
Trimethylaminuria is inherited recessively as a defect in hepatic N-oxidation of dietary derived trimethylamine (TMA) which causes excess excretion of TMA so that affected individuals have a body odour resembling rotten fish. Flavin-containing mono-oxygenase 3 (FMO3) catalyses TMA oxidation and muta