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Developmental variations in metabolic capacity of flavin-containing mono-oxygenase 3 in childhood

✍ Scribed by Makiko Shimizu; Travis Denton; Marie Kozono; John R. Cashman; J. Steven Leeder; Hiroshi Yamazaki


Book ID
108642675
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
736 KB
Volume
71
Category
Article
ISSN
0306-5251

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Trimethylaminuria is inherited recessively as a defect in hepatic N-oxidation of dietary derived trimethylamine (TMA) which causes excess excretion of TMA so that affected individuals have a body odour resembling rotten fish. Flavin-containing mono-oxygenase 3 (FMO3) catalyses TMA oxidation and muta