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Developmental toxicity of the HMG-CoA reductase inhibitor, atorvastatin, in rats and rabbits

โœ Scribed by Dostal, Lori A. ;Schardein, James L. ;Anderson, John A.


Book ID
112219612
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
782 KB
Volume
50
Category
Article
ISSN
0040-3709

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Absorption and disposition of fluvastati
โœ F. L. S. Tse; D. Labbadia ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 464 KB ๐Ÿ‘ 2 views

The absorption and disposition of fluvastatin have been studied in the female rabbit. In naive rabbits receiving a single oral dose (1 mg kg-I) of [3H]fluvastatin, absorption was rapid and amounted to c. 90 per cent compared with an intravenous reference dose. The drug was subject to considerable fi