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Developmental toxicity of N-methyl-2-pyrrolidone administered orally to rats

✍ Scribed by A.M Saillenfait; F Gallissot; I Langonné; J.P Sabaté

Book ID
117450048
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
101 KB
Volume
40
Category
Article
ISSN
0278-6915

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Developmental toxic effects of N-ethyl-2-pyrrolidone administered orally to rats
✍ A. M. Saillenfait; F. Gallissot; J. P. Sabaté 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB

## Abstract The developmental toxicity of __N__‐ethyl‐2‐pyrrolidone (NEP) was studied in Sprague‐Dawley rats after oral administration. Pregnant rats were given NEP at doses of 0 (distilled water), 50, 250, 500 and 750 mg kg^−1^ day^−1^, by gavage (5 ml kg^−1^), on gestational days (GD) 6–20. Mater