## Abstract Analysis of control diploid and polyploid amphibia indicated that cell and nuclear volumes were closely related to their ploidy, so that an increase in ploidy was generally associated with an increase in cell size. This relationship is also believed to occur in mammalian polyploids. How
Developmental potential and behavior of tetraploid cells in the mouse embryo
โ Scribed by Guy S. Eakin; Anna-Katerina Hadjantonakis; Virginia E. Papaioannou; Richard R. Behringer
- Book ID
- 116975383
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 656 KB
- Volume
- 288
- Category
- Article
- ISSN
- 0012-1606
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## Abstract Based on the criteria of relative size and cell surface polarization, subpopulations of outer (larger, polar) and inner (smaller, apolar) blastomeres have been isolated from mouse 16โcell morulae and reaggregated in groups of 16 cells, and the developmental potential of the aggregates h
## Abstract Despite the fact that spontaneous tetraploidy is a rare phenomenon in mice, such embryos may be produced experimentally by a variety of means, though only a very limited degree of postimplantation development has been achieved. Despite this apparent limitation, much data on the rate of