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Developmental expression of multidrug resistance phosphoglycoprotein (P-gp) in the mouse fetal brain and glucocorticoid regulation

โœ Scribed by Sophie Petropoulos; William Gibb; Stephen G. Matthews


Book ID
113505185
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
740 KB
Volume
1357
Category
Article
ISSN
0006-8993

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Developmental expression of p-glycoprote
โœ Matsuoka, Yasuji ;Okazaki, Mitsuhiro ;Kitamura, Yoshihisa ;Taniguchi, Takashi ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 430 KB ๐Ÿ‘ 2 views

P-Glycoprotein (PGP), a product of the multidrug resistance gene (mdr), acts as an adenosine triphosphate-dependent drug efflux system in cells. Initially, PGP was found in cancer cells, but it is now known that PGP is richly distributed in the adult brain. Passage to the central nervous system is l