Cell cycle and developmental control of
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Alan D. Friedman
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Article
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2009
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John Wiley and Sons
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English
β 96 KB
## Abstract Runx1 binds DNA in cooperation with CBFΞ² to activate or repress transcription, dependent upon cellular context and interaction with a variety of coβactivators and coβrepressors. Runx1 is required for emergence of adult hematopoietic stem cells (HSC) during embryonic development and for