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Developmental changes in synaptic membrane fluidity: a comparison of 1,6-Diphenyl-1,3,5-hexatriene (DPH) and 1-[4-(Trimethylamino)phenyl]-6-phenyl-1,3,5-hexatriene (TMA-DPH)

✍ Scribed by Robert J. Hitzemann; R.Adron Harris


Book ID
119100862
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
650 KB
Volume
14
Category
Article
ISSN
0165-3806

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Fluorescence anisotropy measurements are widely used as sensitive indicators of cell membrane fluidity. 1-[4(trimethylamino)phenyl]-6-phenyl hexa-1,3,5-triene (TMA-DPH) is a cationic fluorescent aromatic hydrocarbon that anchors at the lipid-water interface of membrane lipid bilayers. Its uptake int