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Developmental changes in expression of a tumor-associated protein in the rat fetus

✍ Scribed by Steven W. Runge; Saroj Larroya; Dorothy E. Schumm; Thomas E. Webb


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
178 KB
Volume
41
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

✦ Synopsis


Monoclonal antibodies specific for a rat tumor-associated protein cross-react with a similar protein present in the cytosol of the rat fetus. The oncofetal protein exists as two species of approximate molecular weight 50 and 55 kDa which promote the transport of RNA from isolated nuclei. During rat fetal development, the protein first increases in concentration from approximately 12 to 16 days gestation and then drops to non-detectable levels perinatally.


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