Developmental and comparative aspects of posterior medial thalamocortical innervation of the barrel cortex in mice and rats

✍ Scribed by Elizabeth A. Kichula; George W. Huntley

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 584 KB
• Volume: 509
• Category: Article
• ISSN: 0021-9967
• DOI: 10.1002/cne.21776

✦ Synopsis

Abstract

Confocal laser scanning microscope image of a tangential section through layer IV of barrel cortex taken from a rat pup aged postnatal day 6. Thalamocortical axons (TCAs) from the VPM nucleus are labeled by DiD (blue); their terminations form whisker‐related clusters that occupy the barrels. TCAs from the POm nucleus are labeled by DiI (red). By this age, their terminations mostly occupy the intervening septa that separate the barrels, although a few axons are found within the barrels. Thus, by the end of the first postnatal week, an adult‐like pattern of interdigitated thalamocortical projections is largely established. J. Comp. Neurol. 509:239‐258, 2008. © 2008 Wiley‐Liss, Inc.