Development of young rats and rabbits exposed to a strong electric field

✍ Scribed by Prof. R. Portet; J. Cabanes

• Book ID: 102759948
• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 665 KB
• Volume: 9
• Category: Article
• ISSN: 0197-8462
• DOI: 10.1002/bem.2250090109

✦ Synopsis

Body growth and circulating levels of hormones were assessed in young rats and rabbits exposed to a 50-Hz electric field of 50 kV/m. Eight-week-old male rats were exposed 8 h/ day for 4 weeks and rabbits were exposed 16 hlday from the last 2 weeks of gestation to 6 weeks after birth. The body and the organ growth of exposed rats were not statistically different from those of sham-exposed controls. No important differences from controls were observed in plasma levels of corticosterone, TSH, ACTH, and T4 or in adrenal levels of epinephrine, norepinephrine, and corticosterone although T3 was slightly, but significantly, decreased. No large histological changes in the thyroid or adrenals were noted. In rabbits, organ and body wieghts of exposed animals were comparable to those of controls. Plasma levels of various hormones (ACTH, GH, T3, T4, corticosterone, cortisol), serum glucose, triglycerides, and cholesterol were not significantly altered. Adrenal content of cortisol was lower, however, in exposed rabbits. No histological changes of the thyroid or adrenal glands were observed.