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Development of ulcerative colitis under the immunosuppressive effect of cyclosporine

✍ Scribed by Passfall, J. ;Distler, A. ;Riecken, E.O. ;Zeitz, M.

Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
633 KB
Volume
70
Category
Article
ISSN
1432-1440

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✦ Synopsis

In recent studies, cyclosporine has been used for the treatment of both ulcerative colitis and Crohn's disease. The results of these studies were variable. We report on a patient who was treated for 6 years with cyclosporine after kidney transplantation. He developed chronic distal colitis with all the features of ulcerative colitis. An infectious etiology of the colitis was carefully excluded. High-dose treatment with methylprednisolone was required to induce remission. This report shows that immunosuppressive therapy with cyclosporine did not prevent the development of ulcerative colitis in this patient.

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