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Development of tolerance to amnesic effects of chlordiazepoxide in relation to GABAergic and cholinergic neuronal systems

โœ Scribed by Sei-ichi Ishihara; Masayuki Hiramatsu; Tsutomu Kameyama; Toshitaka Nabeshima


Book ID
115888675
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
648 KB
Volume
230
Category
Article
ISSN
0014-2999

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The psychomotor, sedative and memory effects of a sedative, anticholinergic antidepressant (amitriptyline), a sedative antidepressant (trazodone) and placebo were compared in a double-blind, cross-over study with 12 healthy volunteers. Amitriptyline (37.5 mg) and trazodone (100 mg) were administered