Objective determination of the oncolytic
β
Sander Idema; Clemens M. F. Dirven; Victor W. van Beusechem; Jan E. Carette; Rob
π
Article
π
2010
π
John Wiley and Sons
π
English
β 245 KB
## Abstract ## Background Conditionallyβreplicating adenoviruses (CRAds) infect and replicate in tumor cells, releasing viral progeny upon lysis of the cell. This is a dynamic and inherently exponential process and, thus, the assessment of CRAds should incorporate these dynamics. __In vitro__ expe