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Development of the oncolytic conditionally replicating adenoviruses (CRAds)

✍ Scribed by Shanji Fu; Xiuping Yu


Book ID
118473234
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
72 KB
Volume
136
Category
Article
ISSN
0168-1656

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## Abstract ## Background Conditionally‐replicating adenoviruses (CRAds) infect and replicate in tumor cells, releasing viral progeny upon lysis of the cell. This is a dynamic and inherently exponential process and, thus, the assessment of CRAds should incorporate these dynamics. __In vitro__ expe