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Development of the meiotic step in testes of pubertal rats: Comparison between the in vivo situation and under in vitro conditions

✍ Scribed by Marie-HÉlÈne Perrard; Dominique Hue; Christophe Staub; Yves Le Vern; Dominique Kerboeuf; Philippe Durand

Book ID
111661892
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
433 KB
Volume
65
Category
Article
ISSN
1040-452X

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✍ Kristian Linnet 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB

## Abstract A steady‐state model is presented of the metabolism of imipramine. In this model, the __N__‐demethylation and 2‐hydroxylation rates of imipramine were measured with and without the presence of metabolites by using a tritium isotope of imipramine. At an imipramine concentration of 5 μmol