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Development of the Korean version of Alzheimer's Disease Assessment Scale (ADAS-K)

✍ Scribed by J. C. Youn; D. Y. Lee; K. W. Kim; J. H. Lee; J. H. Jhoo; K. U. Lee; J. Ha; J. I. Woo


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
102 KB
Volume
17
Category
Article
ISSN
0885-6230

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✦ Synopsis


Abstract

Objective

The purpose of this study was the development of the Korean Version of Alzheimer's Disease Assessment Scale (ADAS‐K).

Method

ADAS‐K was administrated to 84 AD patients as well as 105 non‐demented control subjects. Three aspects of reliability were tested. To evaluate the validity of ADAS‐K, discriminant validity and concurrent validity were tested. To evaluate the sensitivity of ADAS‐K to disease severity, all subjects, AD patients and control subjects, were grouped by CDR scale and their mean scores on ADAS‐K were compared.

Result

ADAS‐K demonstrated high levels of reliability. Mean ADAS‐K scores for AD patients were significantly different from the control group (p < 0.01). Furthermore, ADAS‐K exhibited significant correlations with other tests and scales (range 0.45–0.85, p < 0.01). In ROC curve analysis, ADAS‐K displayed high diagnostic efficacy and the optimal cut‐off point was selected between 18/19. ADAS‐K was able to discriminate the degree of AD severity according to CDR classification. Our results suggested that ADAS‐K‐cog was sensitive to very mild AD.

Conclusion

We demonstrated that ADAS‐K is a reliable and valid instrument not only for AD diagnosis but also for evaluation of its severity. Copyright © 2002 John Wiley & Sons, Ltd.


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