Development of Synthetic Strategies for the Construction of Pyrido[4,3-d]pyrimidine Libraries – the Discovery of a New Class of PDE-4 Inhibitors
✍ Scribed by Mi-Yeon Jang; Steven De Jonghe; Ling-Jie Gao; Jef Rozenski; Piet Herdewijn
- Book ID
- 102178543
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 218 KB
- Volume
- 2006
- Category
- Article
- ISSN
- 1434-193X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
Experiments to effect Sonogashira (Ph 3 P) 2 Cl 2 Pd-CuI-based coupling of 3-methylpentyn-3-ol at C-2 of a 2-iodo-6-thiopurine derivative, bound via the sulfur atom to a Merrifield resin failed. In contrast, the analogous reaction with Pd(dppe)Cl 2 and trans-di(m-acetato)bis[o-(di-o-tolylphosphino)b