Carbon-14 radiosynthesis of combretastat
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Rodney T. Brown; Victor L. Murrell; Austin McMordie; Madhavi Sriram; Kevin G. Pi
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Article
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2009
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John Wiley and Sons
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French
⚖ 116 KB
## Abstract The natural product combretastatin A‐1 (CA1) is isolated from the African bush willow tree, a member of the __Combretaceae__ family. CA1 has important medicinal value, due in part to its ability to inhibit tubulin assembly. The prodrug combretastatin A‐1 diphosphate (CA1P; OXi4503) is c