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Development of sustained release matrix tablets of didanosine containing methacrylic and ethylcellulose polymers

✍ Scribed by Carla Sánchez-Lafuente; M. Teresa Faucci; Mercedes Fernández-Arévalo; Josefa Álvarez-Fuentes; Antonio M. Rabasco; Paola Mura


Book ID
108454059
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
409 KB
Volume
234
Category
Article
ISSN
0378-5173

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Sustained-release and swelling character
✍ T. Quinten; T. De Beer; F. O. Onofre; G. Mendez-Montealvo; Y. J. Wang; J. P. Rem 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB

Sustained-release matrix tablets were developed by injection moulding using metoprolol tartrate (MPT) and ethylcellulose (EC) as sustained-release agent. Dibutyl sebacate was selected as plasticiser. The influence of matrix composition, plasticiser concentration, and drug load on drug release was ev