✦ LIBER ✦

Development of steroid sulfatase inhibitors

✍ Scribed by L.W. Lawrence Woo; Atul Purohit; Barry V.L. Potter

Book ID: 116734957
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 565 KB
Volume: 340
Category: Article
ISSN: 0303-7207
DOI: 10.1016/j.mce.2010.12.035

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## Abstract Steroid sulfatase (STS) regulates the local production of estrogens and androgens from systemic precursors in several tissues. The enzyme catalyzes the hydrolysis of the sulfate esters of 3‐hydroxy steroids, which are inactive transport or precursor forms of the active 3‐hydroxy steroid