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Development of protective immunity against cutaneous leishmaniasis is dependent on STAT1-mediated IFN signaling pathway

✍ Scribed by Lucia E. Rosas; Tracy Keiser; Ryan Pyles; Joan Durbin; Abhay R. Satoskar


Book ID
102163541
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
171 KB
Volume
33
Category
Article
ISSN
0014-2980

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STAT-4 mediated IL-12 signaling pathway
✍ Luisa M. Stamm; Anjali A. Satoskar; Sudip K. Ghosh; John R. David; Abhay R. Sato 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 2 views

Recent studies have demonstrated that two IL-12 signaling pathways, a STAT 4 -dependent and STAT4 -independent, are involved in the development of a Th1-like response. To determine their roles in the development of protective immunity against Leishmania major, we monitored progression of cutaneous L