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Development of Potent Thrombin Receptor Antagonist Peptides

✍ Scribed by Bernatowicz, Michael S.; Klimas, Clifford E.; Hartl, Karen S.; Peluso, Marianne; Allegretto, Nick J.; Seiler, Steven M.

Book ID
127357073
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
301 KB
Volume
39
Category
Article
ISSN
0022-2623

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## Abstract Calcitonin gene‐related peptide (CGRP), a potent dilator of cerebral and dural vasculature, is known to be elevated in plasma and cerebral spinal fluid during migraine attacks. Selective blockade of the CGRP receptor offers the promise of controlling migraine headache more effectively a