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Development of New Chiral Auxiliary Derived from (S)-(-)-Phenylethylamine for a Synthesis of Enantiopure (R)-2-Propyloctanoic Acid.

✍ Scribed by Tomoyuki Hasegawa; Hisashi Yamamoto


Publisher
John Wiley and Sons
Year
2003
Weight
134 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


📜 SIMILAR VOLUMES


A Simple Stereoselective Synthesis of En
✍ José M. Andrés; Ignacio Herráiz-Sierra; Rafael Pedrosa; Alfonso Pérez-Encabo 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB 👁 2 views

Chiral, nonracemic 2-substituted pyrrolidines and piperidines were prepared in high ee and moderate to good chemical yields in three steps from (R)-phenylglycinol and γ-or δchloroketones. The key step of the synthesis was the stereo-