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Development of New and Selective Trypanosoma cruzi trans-Sialidase Inhibitors from Sulfonamide Chalcones and Their Derivatives

✍ Scribed by Jin Hyo Kim ; Hyung Won Ryu; Jae Hoon Shim; Ki Hun Park; Stephen G. Withers

Book ID
101820675
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
277 KB
Volume
10
Category
Article
ISSN
1439-4227

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The protozoan parasite Trypanosoma cruzi is the causative agent of human American trypanosomiasis, also known as Chagas disease, which in its chronic form can lead to severe debilitation and ultimately death. [1] According to World Health Organization (WHO) estimates, 16 to 18 million people were in