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Development of N-butyl-N-(hydroxybutyl)-nitrosamine-induced tumors in the partially resected, proliferating rat urinary bladder in dependence upon the time of onset of stimulated DNA synthesis

✍ Scribed by Kunze, E. ;K�nnecke, B. ;Nienaber, C.


Book ID
104712964
Publisher
Springer
Year
1990
Tongue
English
Weight
485 KB
Volume
18
Category
Article
ISSN
0300-5623

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Chemotherapeutic agents were evaluated for effect on the development of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) in male Wistar strain rats. Seven hundred and two rats were given 0.05% BBN in drinking water for 8 weeks. After BBN treatment, the animals were divi