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Development of methodology for the rapid incorporation of carbon-13 into 1,2,4-triazolo systems from carbon dioxide

✍ Scribed by William R. Banks; George A. Digenis


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
157 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis


An in situ production of C-13 acetyl chloride and subsequent reaction with amidrazones affords anxiolytic 1,2,4-triazolobenzodiazepines in reaction times suitable for labelling with carbon-11 (tl,2=20.4 min).