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Development of metabotropic glutamate receptor subtype selective drugs

โœ Scribed by D.D. Schoepp; J. Cartmell; B.G. Johnson; R.A. Wright; S. Andis; C.R. Salhoff; J.P. Tizzano; P.L. Ornstein; J.A. Monn


Book ID
118601273
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
218 KB
Volume
9
Category
Article
ISSN
0924-977X

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โœ Dawei Ma ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 354 KB

L-Glutamate, a major neurotransmitter in excitatory synaptic pathways of the mammalian central nervous system (CNS)(1), plays an important role in many integrative brain functions (1-4). Glutamate receptors have been classified into two distinctive groups termed ionotropic and metabotropic receptors