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Development of knowledge-based system for predicting the stability of proteins upon point mutations

โœ Scribed by Liang-Tsung Huang; Lien-Fu Lai; Chao-Chin Wu; M. Michael Gromiha

Book ID
113816517
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
691 KB
Volume
73
Category
Article
ISSN
0925-2312

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๐Ÿ“œ SIMILAR VOLUMES

The linear interaction energy method for
The linear interaction energy method for the prediction of protein stability changes upon mutation
โœ Lauren Wickstrom; Emilio Gallicchio; Ronald M. Levy ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 559 KB

## Abstract The coupling of protein energetics and sequence changes is a critical aspect of computational protein design, as well as for the understanding of protein evolution, human disease, and drug resistance. To study the molecular basis for this coupling, computational tools must be sufficient