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Development of iodized oil emulsion for use as a contrast agent in X-ray computed tomography of the liver and spleen


Book ID
117077763
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
151 KB
Volume
42
Category
Article
ISSN
0009-9260

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The introduction of a lipophilic moiety into the gadolinium chelate Gd-DTPA (dimeglumine gadopentetate, Magnevist) yielded Gd-EOB-DTPA (short form), which has potential as a magnetic resonance contrast agent for liver mass screening. The pharmacokinetics of Gd-EOB-DTPA in rats is nonlinear because a