𝔖 Bobbio Scriptorium
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Development of intestinal epithelial cell lines using a transgenic mouse

✍ Scribed by R. H. Whitehead; J. L. Joseph


Book ID
105026221
Publisher
Springer
Year
1995
Tongue
English
Weight
656 KB
Volume
17
Category
Article
ISSN
1573-0603

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A tk+/mouse embryonic stem (ES) cell line, designated 1G2, has been created in which one allele of the thymidine kinase (tk) gene was inactivated by targeted homologous recombination. This line is an analog of the mouse lymphoma tk+/-L5 178Y cell line, which is used widely to assess the mutagenicity