𝔖 Bobbio Scriptorium
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Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulators

✍ Scribed by C Joel Funk; Ashley S Davis; Janet A Hopkins; Kim M Middleton

Book ID
108047669
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
569 KB
Volume
329
Category
Article
ISSN
0003-2697

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We developed a 96-well microtiter-plate highthroughput screening (HTS) assay for the detection of modulators of transcription. This HTS assay consists of three steps: (1) the in vitro transcription reaction; (2) modification and hybridization of RNA products; and (3) washing and quantification. Dur