𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Development of high concentration protein biopharmaceuticals: The use of platform approaches in formulation development

✍ Scribed by Nicholas W. Warne


Book ID
116438465
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
162 KB
Volume
78
Category
Article
ISSN
0939-6411

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Challenges in the development of high pr
✍ Steven J. Shire; Zahra Shahrokh; Jun Liu πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 197 KB

Development of formulations for protein drugs requiring high dosing (in the order of mg/kg) may become challenging for solubility limited proteins and for the subcutaneous (SC) route with <1.5 mL allowable administration volume that requires >100 mg/mL protein concentrations. Development of high pro

Development of a microflow digital imagi
✍ Klaus Wuchner; Jochen BΓΌchler; Rene Spycher; Paul Dalmonte; David B. Volkin πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 260 KB

The development of a Microflow digital imaging (MDI) method to detect and monitor protein particulates in a high concentration IgG1 monoclonal antibody formulation is presented. The MDI assay was optimized and qualified as a characterization assay in terms of accuracy and precision of particle size