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Development of hexachlorobenzene porphyria in rats: Time sequence and relationship with lipid peroxidation

✍ Scribed by Visser, O.; van den Berg, J.W.O.; Edixhoven-Bosdijk, A.; Koole-Lesuis, R.; Rietveld, T.; Wilson, J.H.P.


Book ID
122483575
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
508 KB
Volume
27
Category
Article
ISSN
0278-6915

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Both human porphyria cutanea tarda and experimental hexachlorobenzene-induced porphyria are associated with hepatic injury and are potentiated by excess hepatic iron. The mechanisms whereby cellular injury occurs and the synergistic role of iron overload are unknown. In the present experiments, we s