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Development of Efficient Energy Function for Protein-Small Molecule Interactions in Medusadock

โœ Scribed by Nedumpully Govindan, Praveen; Ding, Feng


Book ID
122143337
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
34 KB
Volume
106
Category
Article
ISSN
0006-3495

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Small-molecule proteinโ€“protein interacti
โœ Peter Buchwald ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 285 KB

## Abstract As the ultimate function of proteins depends to a great extent on their binding partners, proteinโ€“protein interactions (PPIs) represent a treasure trove of possible new therapeutic targets. Unfortunately, interfaces involved in PPIs are not wellโ€suited for effective small molecule bindi