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Development of chemopreventive agents for lung and upper aerodigestive tract cancers


Book ID
123110147
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
159 KB
Volume
11
Category
Article
ISSN
0169-5002

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Intermediate biomarkers in upper aerodig
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Chemoprevention trials in lung and upper aerodigestive tract (UADT) cancer are guided by the field cancerization hypothesis. Inhaled carcinogens place the entire epithelial lining at risk for the development of cancer. The hypothesis is supported by the occurrence of premalignant lesions, such as le