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Development of Carbohydrate-Based Scaffolds for Restricted Presentation of Recognition Groups. Extension to Divalent Ligands and Implications for the Structure of Dimerized Receptors

✍ Scribed by Murphy, Paul V.; Bradley, Helena; Tosin, Manuela; Pitt, Nigel; Fitzpatrick, Geraldine M.; Glass, W. Kenneth

Book ID
126841594
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
342 KB
Volume
68
Category
Article
ISSN
0022-3263

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## Abstract In this study, we evaluated the applicability of ligand‐based and structure‐based models to quantitative affinity predictions and virtual screenings for ligands of the β~2~‐adrenergic receptor, a G protein‐coupled receptor (GPCR). We also devised and evaluated a number of consensus mode