Development of Biisoquinoline-Based Chiral Diaminocarbene Ligands: Enantioselective S N 2‘ Allylic Alkylation Catalyzed by Copper−Carbene Complexes
✍ Scribed by Seo, Hwimin; Hirsch-Weil, Dimitri; Abboud, Khalil A.; Hong, Sukwon
- Book ID
- 120017588
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 168 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
New P,N ligands prepared from (S)-2-alkyl-2-aminoethylphosphines and a-substituted pyridines are efficient chiral ligands for the copper-catalyzed conjugate addition of diethylzinc to 2-cyclohexen-1-one and chalcone. The best result (90-91% ee) for the cyclohexenone was obtained with Cu(OTf) 2 (0.7-
a b s t r a c t [( 5 -C 5 R 5 )Ru(N-N\*)(NCMe)]PF 6 (R = H, N-N\* = (Sa)-1, 5; (Sa)-2, 6; (R,R)-3, 7; (R,R)-4; 8; R = Me, N-N\* = (Sa)-1, 9) complexes containing N-N\* bulky chiral ligands of different rigidity and flexibility were synthesized by reacting the precursor [( 5 -C 5 R 5 )Ru(NCMe) 3 ]PF