Development of autoimmune exocrinopathy resembling Sjögren's syndrome in adoptively transferred mice with autoreactive CD4+ T cells

Correlation of increased susceptibility

Correlation of increased susceptibility to apoptosis of CD4+ T cells with lymphocyte activation and activity of disease in patients with primary Sjögren's syndrome

✍ Margit Zeher; Péter Szodoray; Edit Gyimesi; Zsuzsa Szondy 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB 👁 2 views

Objective. To investigate whether a change in the CD95-related apoptosis of T lymphocytes might have a share in the development of the disease in patients with primary Sjo ¨gren's syndrome (SS). Methods. Two-color cytometric analysis was used to study the phenotype of freshly separated mononuclear