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Development of appropriate equations for physiologically based pharmacokinetic modeling of permeability-limited and flow-limited transport

✍ Scribed by Matthew D. Thompson; Daniel A. Beard


Publisher
Springer
Year
2011
Tongue
English
Weight
504 KB
Volume
38
Category
Article
ISSN
1573-8744

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## Abstract For clinical dynamic contrast‐enhanced (DCE) MRI studies, it is often not possible to obtain reliable arterial input function (AIF) in each measurement. Thus, it is important to find a representative AIF for pharmacokinetic modeling of DCE‐MRI data when individual AIF (Ind‐AIF) measurem