We have determined the molecular basis of hypoxanthine-guanine phosphoribosyltransferase (HPRT; HPRT1) deficiency in eight Lesch-Nyhan patients and in five partially HPRT deficient patients with mild to severe neurologic symptoms. Eight of these thirteen mutations have not been previously described.
β¦ LIBER β¦
Development of antischistosomal agents: Inhibitors of hypoxanthine-guanine phosphoribosyltransferase
β Scribed by Dr. Arun L. Jadhav; Shahrokh Sirossian
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 444 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0272-4391
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The X-linked hypoxanthine-guanine phosphoribosyl-respectively. These data were similar to the reported transferase (hprt) gene is a target of analyses of in values. The mean MFs in the nine colon cancer pavivo mutation frequencies in circulating T-lympho-tients (10.6 { 7.3 1 10 06 ) were not signifi