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Development of an LC Method for Simultaneous Analysis of Cinnamic Acid and Paeonol in Rat Plasma, and Its Application to a Pharmacokinetic Study after Intragastric Administration of Guizhi–Fuling Capsule

✍ Scribed by Xiaoxia Gao; Zhiguo Yu; Yunli Zhao; Lei Men; Qi Wang; Zhenzhong Wang; Xiaohui Chen; Wei Xiao; Kaishun Bi


Book ID
111791642
Publisher
Springer
Year
2009
Tongue
English
Weight
285 KB
Volume
70
Category
Article
ISSN
0009-5893

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✍ Kuldeep Sharma; Murugesh Kandaswamy; Chandan Mithra; Ashok Kumar Meena; Sanjeev 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 628 KB

## ABSTRACT A highly sensitive and specific LC‐MS/MS‐ESI method was developed for simultaneous quantification of albenadazole (ABZ) and ricobendazole (RBZ) in rat plasma (50 μL) using phenacetin as an internal standard (IS). Simple protein precipitation was used to extract ABZ and RBZ from rat plas