๐”– Bobbio Scriptorium
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Development of an intact hepatocyte activation system for routine use with the mouse lymphoma assay

โœ Scribed by Brock, Karen H. ;Moore, Martha M. ;Oglesby, Linda A.

Publisher
Wiley (John Wiley & Sons)
Year
1987
Weight
596 KB
Volume
9
Category
Article
ISSN
0192-2521

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In previously described activation systems [Clive D, Spector : Mutat Res 31:17-291 for the mouse lymphoma mutation assay the cofactor isocitrate is rapidly exhausted and the resultant loss of NADPH can halt metabolic processes. Presented here are data obtained with a nontoxic b'olance of NADP (1.4 m