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Development of an Asymmetric Hydrogenation Route to ( S )- N -Boc-2,6-dimethyltyrosine
✍ Scribed by Praquin, Céline F. B.; de Koning, Pieter D.; Peach, Philip J.; Howard, Roger M.; Spencer, Sarah L.
- Book ID
- 118144674
- Publisher
- American Chemical Society
- Year
- 2011
- Tongue
- English
- Weight
- 747 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1083-6160
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📜 SIMILAR VOLUMES
We describe the photoinduced addition of methanol to 5(S)-5-triisopropylsiloxymethyi--N-boc-dihydropyrrole-2(SH)-one to produce 5(S)-5-triisopropylsiloxymethyl-4( S)-hydroxymethylpyrrolidine-2-one, and conversion of this into a variety of 4(S), 5(S)-pyrrolidine-2-ones. Photoinduced addition of metha
The title compound, C 39 H 39 N 3 O 4 , although having potential C 2 molecular symmetry, crystallizes as an asymmetric conformer, due to a couple of strong intramolecular hydrogen bonds involving hydroxyl groups and a pyridine N atom. This geometrical feature explains why this compound behaves as a