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Development of an analytical methodology from toxicokinetic to clinical studies for the anti-migraine drug frovatriptan

โœ Scribed by L. Laugher; R. Briggs; J. Doughty; T. A. G. Noctor

Publisher
Springer
Year
2000
Tongue
English
Weight
699 KB
Volume
52
Category
Article
ISSN
0009-5893

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โœ Sheila R. Knaub; Ming F. Chang; Craig E. Lunte; Elizabeth M. Topp; Christopher M ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 703 KB

An automated system utilizing microdialysis sampling, intermittent dosing, and liquid chromatographic analysis was assembled in order to study the partitioning of lomefloxacin, a fluoroquinolone antimicrobial, into human erythrocytes in vitro. The apparent erythrocyte:buffer partition coefficient wa