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Development of a Working Model of the Active Site in Bovine Lens Leucine Aminopeptidase: A Density Functional Investigation

โœ Scribed by Stefan Erhardt; Jennie Weston


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
85 KB
Volume
3
Category
Article
ISSN
1439-4227

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A number of previous studies have determined that a metalloenzyme active site is inherently determined by the ligands and metal and only weakly perturbed by the surrounding protein environment. This conclusion is now being tested for several families of bimetallic enzymes. Metal substitution is exam