## Abstract A broad dental toxicology screening program has been initiated to develop suitable testing methods for new dental materials or products which presently are not considered as drugs. In the report presented here, 42 materials or products have been included in an acute toxicity screening p
Development of a toxicity evaluation program for dental materials and products. II. Screening for systemic toxicity
โ Scribed by Lawrence, W. H. ;Malik, M. ;Autian, J.
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 956 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0021-9304
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
A series of systemic toxicity tests for various types of compounds are presented with illustrative data and discussed in regard to their relevance as potential screening tests for dental compounds and products. In developing and marketing a new dental material, it is important not only to ensure safety for the patient but also for the dentist, dental assistant, and laboratory worker who routinely handles and uses the product. Data are presented on a number of commercially available dental products as well as various chemical entities, which were tested by one or more of the methods described.
๐ SIMILAR VOLUMES
## Abstract The A.D.A. acute systemic test for type II, class 11 materials defines compliance on the basis of fewer than 50% mortality at 2 weeks. Histopathologic criteria were developed from pilot study data to evaluate the effects of these materials. In this double blind study, the frequency of h
## Abstract A multiagency effort is underway to develop whole sediment toxicity identification evaluation (TIE) methods. Whole sediment TIE methods will be critical tools for characterizing toxicity at hazardous waste sites (e.g., Superfund sites) and in the conduct of environmental risk assessment
An attempt has been made to present toxicological results obtained by a biological evaluation method in a simple and comprehensive way. The calculation of a toxicity index which expresses mortality rates as a function of the very important time factor is proposed. Additionally it is shown how such a