✦ LIBER ✦

Development of a thermosensitive grafted drug delivery system—synthesis and characterization of NIPAAm-based grafts and hydrogel structure

✍ Scribed by Induvadana Ankareddi; Christopher S. Brazel

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 762 KB
Volume: 120
Category: Article
ISSN: 0021-8995
DOI: 10.1002/app.33272

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Physical characterization of a chitosan-

Physical characterization of a chitosan-based hydrogel delivery system

✍ Jinjiang Li; Zhenghe Xu 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB

Hydrogel formation from a mixture of biocompatible chitosan, beta-glycerol phosphate, and hydroxyethyl cellulose was studied. The rheological properties of the formed hydrogels were examined using a Bohlin VOR rheometer. The effect of hydrogel composition and temperature on both the gelation rate an

Synthesis and characterization of in sit

Synthesis and characterization of in situ chitosan-based hydrogel via grafting of carboxyethyl acrylate

✍ Mi-Sook Kim; Yoon-Jeong Choi; Insup Noh; Giyoong Tae 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

## Abstract We developed and characterized a novel __in situ__ chitosan‐poly(ethylene oxide) (PEO) hydrogel via two steps: 2‐carboxyethyl acrylate molecules were grafted to the primary amine functional groups in chitosan in the first step and then Michael type addition reaction was processed betwee

Biodegradable in situ gel-forming contro

Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL–PEG–PCL hydrogel: Part 1—synthesis, characterization, and acute toxicity evaluation

✍ Chang Yang Gong; Shuai Shi; Peng Wei Dong; Bing Yang; Xiao Rong Qi; Gang Guo; Yi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 489 KB

Toxicity evaluation of biodegradable and

Toxicity evaluation of biodegradable and thermosensitive PEG-PCL-PEG hydrogel as a potential in situ sustained ophthalmic drug delivery system

✍ HongBo Yin; ChangYang Gong; Shuai Shi; XuYang Liu; YuQuan Wei; ZhiYong Qian 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 880 KB

## Abstract In this work, a biodegradable poly(ethylene glycol)‐poly(ε‐caprolactone)‐poly (ethylene glycol) (PEG‐PCL‐PEG, PECE) triblock copolymer was successfully synthesized, which was flowing sol at low temperature and turned to nonflowing gel at body temperature. The toxicity evaluation of PECE

Synthesis, Characterization and Drug Rel

Synthesis, Characterization and Drug Release Behavior of pH-Responsive O-carboxymethyl Chitosan-graft-poly(N-vinylpyrrolidone) Hydrogel Beads

✍ Liwei Ma; Mingzhu Liu; Jun Chen; Hongliang Liu; Dapeng Cui; Chunmei Gao 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 709 KB

Acute toxicity evaluation of biodegradab

Acute toxicity evaluation of biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PEG-PCL-PEG hydrogel

✍ Chang Yang Gong; Qin Jie Wu; Peng Wei Dong; Shuai Shi; Shao Zhi Fu; Gang Guo; Hu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 885 KB

## Abstract In this work, a biodegradable poly(ethylene glycol)‐poly(ε‐caprolactone)‐poly (ethylene glycol) (PEG‐PCL‐PEG, PECE) triblock copolymer was successfully synthesized. The aqueous solution of such PECE copolymer displayed special sol–gel–sol transition as temperature increase, which is a f