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Development of a sensitive and reliable LC-MS-MS assay to quantitate dimethyl benzoylphenylurea (BPU) in human plasma

Book ID
117659463
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
139 KB
Volume
38
Category
Article
ISSN
0959-8049

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Development and validation of a highly sensitive LC-MS/MS method for quantitation of dexlansoprazole in human plasma: application to a human pharmacokinetic study
✍ Kishore Kumar Hotha; D. Vijaya Bharathi; B. Jagadeesh; L. K. Ravindranath; K. N. πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 311 KB πŸ‘ 3 views

## ABSTRACT A highly sensitive, specific and simple LC‐MS/MS method was developed for the simultaneous estimation of dexlansoprazole (DEX) with 50 μL of human plasma using omeprazole as an internal standard (IS). The API‐4000 LC‐MS/MS was operated under multiple reaction‐monitoring mode using elect